Preheat the grill to 275 degrees and set for indirect heat. Place the seasoned beef shank vertically on the grill and let it smoke for about 3 hours.
In a large foil pan, add sliced onion, minced garlic, ideally beef broth, Worcestershire sauce and more hot sauce.
Place the smoked beef shank vertically into the braise and pour an entire can of beer for that hoppy flavor. Cover the entire thing tightly with foil and back on the grill it goes.
Remove once the beef is fork tender. Shred and serve.